eSHa 2000 vs PolyGuard: check formulation and precautions
By Richard James · Manufacturer sources reviewed 28 October 2026
These are different medicines, not regional versions of the same recipe. Matching the symptom words on their webpages does not establish an equivalent dose or make one a stronger next step.
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Do not transfer the units or schedule
Seachem's PolyGuard is a multi-ingredient powder with its own included measure and repeat schedule. A drop amount from the eSHa 2000 calculator cannot be converted into a PolyGuard spoonful. DoseMyTank does not provide a PolyGuard calculator.
The treatment setup matters
Seachem instructs removal of invertebrates and changes to chemical filtration, UV and ozone for PolyGuard. Its FAQ generally advises against mixing medicines. Those instructions are product-specific; do not import a combination permitted by eSHa into a PolyGuard course.
Read the reviewed eSHa 2000 guide for its own standard-course limits. Read the supplied PolyGuard label directly for that product, including its measures and maximum course.
Ask a useful question before switching
Record the uncertain symptoms, water results, treatment history and response. Ask an appropriate fish-health adviser what evidence supports the proposed treatment and how to handle any transition. This article does not establish that either product treats every ulcer, fungus-like patch or damaged fin.
Sources and review scope
eSHa 2000 directions · Seachem PolyGuard directions. Reviewed 28 October 2026. Published manufacturer directions and editorial claims; not an independent clinical or efficacy assessment.